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Department of Chemistry

Chemistry is an experimental science. Ideas explored in the classroom come to life when tested in the laboratory. At PACE, students strive to understand the nature of the chemical world around them. Chemistry students ask themselves a variety of questions: Why do chemical reactions occur? How do they occur? What are the fundamental theories that lie behind chemical reactions? How can we make use of these reactions in our everyday world?

Our department has well qualified and dedicated staff members and technical staff. The department has been maintaining excellent results in both theory and practical examinations since establishment of the college. The staff members play multifaceted role of a teacher, mentor and friend. They involve themselves in the welfare activities of the students.

We at our department appreciate the intellectual excellence and creativity of the students and more importantly truthfulness, sincerity, gentleness and faith in god.

Message from HOD

Chemistry is an experimental science. Ideas explored in the classroom come to life when tested in the laboratory. At PACE, students strive to understand the nature of the chemical world around them. Chemistry students ask themselves a variety of questions: Why do chemical reactions occur? How do they occur? What are the fundamental theories that lie behind chemical reactions? How can we make use of these reactions in our everyday world?

Our department has well qualified and dedicated staff members and technical staff. The department has been maintaining excellent results in both theory and practical examinations since establishment of the college. The staff members play multifaceted role of a teacher, mentor and friend. They involve themselves in the welfare activities of the students.

We at our department appreciate the intellectual excellence and creativity of the students and more importantly truthfulness, sincerity, gentleness and faith in god.

Course Structure

  • Semester 1
  • Advanced Calculus and Numerical Methods (Basic Science Courses)
  • Engineering Chemistry (Basic Science Courses)
  • C Programming for Problem Solving (Engineering Science Courses)
  • Basic Electronics (Engineering Science Courses)
  • Elements of Mechanical Engineering (Engineering Science Courses)
  • Technical English-II (Humanity, Social Science and Management Courses)
  • Semester 2
  • Calculus and Linear Algebra (Basic Science Courses)
  • Engineering Physics (Basic Science Courses)
  • Basic Electrical Engineering (Engineering Science Courses)
  • Elements of Civil Engineering and Mechanics (Engineering Science Courses)
  • Engineering Graphics (Engineering Science Courses)
  • Technical English-I (Humanity, Social Science and Management Courses)
  • Ms. Razeena Begam

    Assistant Professor & HOD

    Qualification : M.Sc
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  • Ms. Razeena Begam

    Assistant Professor & HOD

    M.Sc

    razeena_chemistry@pace.edu.in

    Educational Details

    Degree : B.Sc.
    Year : 1999
    University : Mangalore University
    PG Degree : MSc Chemistry
    Year : 2002
    University : Mangalore University

    Teaching Experience

    15 Years

    Specialization PG

    Chemistry

    Subjects teaching at Under Graduate level

    Chemistry

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  • Ms. Supriya Bangera

    Assistant Professor

    Qualification : M.Sc
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  • Ms. Supriya Bangera

    Assistant Professor

    M.Sc

    supriya_chem@pace.edu.in

    Educational Details

    Degree : B.Sc
    Year : 2006
    University : St Aloysius College, Mangaluru
    PG Degree : M.Sc
    Year : 2008
    University : Mangalore University, Mangalagangothri
    Doctoral Degree : (Pursuing)
    Year :
    University : VTU

    Teaching Experience

    14

    Specialization Ph.D

    Corrosion Inhibition Studies

    Specialization PG

    Applied Chemistry

    Subjects teaching at Under Graduate level

    Engineereing chemistry

    International journals

    Aqueous Extract of MacarangaPeltata Leaves—Green Corrosion Inhibitor for Mild Steel in Hydrochloric Acid Medium." Surface Engineering and Applied Electrochemistry 56 (2020): 259-266.
    Corrosion Inhibitive Property of Environmentally Benign Syzygiumjambos Leaf Extract on Mild Steel in 1 M HCl." Journal of Failure Analysis and Prevention 20 (2020) https://doi.org/10.1007/s11668-020-00869-y
    Inhibition Effect of Thiourea Derivative for Mild Steel Corrosion in Acid Medium: Experimental and Theoretical Studies" Journal of Bio- and Tribo-Corrosion (2021) 7:47.
    A Sustainable and Green Approach to Corrosion Inhibition of MildSteel by Rangoon Creeper Flower Extractin 1 M HCl” Surface Engineering and Applied Electrochemistry 57(2021) 455–465. 
    Averrhoa bilimbi Leaf Extract as a Potent and Sustainable Inhibitor for Mild Steel in 1 M HCl Medium: Experimental and DFT Enumeration” Chemistry of Africa (2022) https://doi.org/10.1007/s42250-022-00313-8
    Hemigraphis colorata (HC) Leaves Extract as Effectual Green Inhibitor for Mild Steel Corrosion in 1M HCl” Biointerface Research in Applied Chemistry (2022) https://doi.org/10.33263/BRIAC132.200
    An experimental, theoretical, and spectral approach to evaluating the ef_ect of eco-friendly Oxalis stricta leaf extract on the corrosion inhibition of mild steel in 1 N H2SO4 medium. Journal of the Iranian Chemical Society (2021) https://doi.org/10.1007/s13738-021-02422-6
    An integrated electrochemical and theoretical approach on the potency of Senegalia rugata leaf extract as a novel inhibitor for mild steel in acidic medium. Journal of Applied Electrochemistry (2022) https://doi.org/10.1007/s10800-021-01631-4

    Papers Presented in National Conference

    Presented a paper on “A study on the corrosion inhibition of mild steel in acidic medium by Macarangapeltata leaves extract under varying condition : at Govinda Das  college , Surathkal,   a UGC sponsored national conference on Synthetic, Spectroscopic and Structural chemistry.

    Papers Presented in International Conference

    Presented a paper on “Investigation of corrosion inhibition behaviour of bilimbli extracts leaves extract on mild steel in hydrochloric acid medium” at Mangalore University, Mangalagangothri, Konaje, an international conference on Advances in Chemical and Materials Science

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  • Dr. Sareen Sheik

    Assistant Professor

    Qualification : M.Sc ,Ph.D
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  • Dr. Sareen Sheik

    Assistant Professor

    M.Sc ,Ph.D

    sareen.chem@pace.edu.in
    Assistant Professor and Research Coordinator, Dept. of Chemistry

    Educational Details

    Degree : Botany, Zoology and Chemistry
    Year :
    University :
    PG Degree : Chemistry
    Year :
    University :
    Doctoral Degree : Polymer Biocomposites
    Year :
    University :

    Specialization Ph.D

    Polymer Biocomposites

    Specialization PG

    Chemistry

    National journals

    Sana Sheik, Sareen Sheik, K.R. Chandrashekar “ Study on the biocompatibility properties of chitosan PVA blend films loaded with extract of endophytic fungus Lasiodiplodia theobromae” Proceedings of the International Conference on Recent Advances in Materials Science and Biophysics-RAMSB 2018)

    International journals

    1. Sareen Sheik, Sana Sheik, Rajesha Nairy, G.K. Nagaraja, Ashwini Prabhu , P.D. Rekha and Kalappa Prashantha, “Study on the morphological and biocompatible properties of chitosan grafted silk fibre reinforced PVA films for tissue engineering applications” International Journal of Biological Macromolecules. 116,(2018) 45-53 (IF-3.9, Elsevier).
    2. Sareen Sheik, Sana Sheik, G.K. Nagaraja, K.R. Chandrashekar, “Thermal, morphological and antibacterial properties of chitosan grafted silk fibre-reinforced PVA composite films” Materials Today Proceedings, 5, (2018) 21011-21017 (Elsevier).
    3. Sareen Sheik, G.K. Nagaraja and Kalappa Prashantha “Effect of silk fibre on the structural, thermal and mechanical properties of PVA/PVP composite films”, Polymer Engineering and Science, 58, (2018) 1923-1930 (IF- 1.551, Wiley).
    4. Sareen Sheik, G.K. Nagaraja, Jagadish Naik, R.F. Bhajanthri, “Development and characterization study of silk fibre reinforced poly (vinyl alcohol) composites”, International Journal of Plastics Technology, 21, (2017) 108-122 (Springer).

    Papers Presented in National Conference

    1. Sareen Sheik and G.K. Nagaraja, “Antibacterial properties of Chitosan grafted silk fibre reinforced PCL films” in the National Conference on Reaching the Unreached through Science and Technology (NCSTRU-2017), organized by Mangalore University, Mangalagangothri. held on 8th  and 9th  September 2017.
    2. Sareen Sheik and G.K. Nagaraja, “Degradation study of PCL films reinforced with Chitosan grafted silk fibre” in the National level symposium (SYMBIOT-17), organized by Manipal Institute of Technology, Manipal held on 11th  and 12th  August 2017.
    3. Sareen sheik and G.K. Nagaraja, “Thermal, Morphological and Degradation Characteristics of Silk fibre Reinforced PVA Composite Films” in the National Conference on Pure and Applied Chemistry (NACOPAC-2014), organized by the Dept. of Studies in Chemistry, Manasagangothri, Mysore held on 29th to 31st December 2014.

    Papers Presented in International Conference

    1. Sareen Sheik, Sana Sheik and G.K. Nagaraja, “ Effect of Gamma Radiation on the properties of Chitosan grafted silk fibre reinforced PCL films” at the  second International Conference on Advanced Materials and Technology, ICMAT-20,   organized by JSS Science and Technology University, Mysore, on 16th -18th January, 2020.
    2. Sareen Sheik and G.K. Nagaraja, “Study of Chitosan grafted silk fibre reinforced PVA films for potential biomedical applications” in the International Conference on Emerging Trends in Chemical Sciences (ICETCS-2017), organized by Department of Chemistry, Manipal Institute of Technology, Manipal held on 14th to 16th September 2017.
    3. Sareen Sheik and G.K. Nagaraja, “Preparation and properties of chitosan grafted silk fibre reinforced composite films ” in the International Conference on Green Chemistry and Nanotechnology Opportunities and Challenges, organized by St. Aloysius College, Mangaluru, held on 27th  and 28th  February 2017.
    4. Sareen Sheik, Sana Sheik, G.K. Nagaraja and K.R. Chandrashekar, “Thermal, morphological and antibacterial properties of chitosan grafted silk fibre-reinforced PVA composite films” in the International Conference on Smart Engineering Materials (ICSEM-2016), organized by R.V. College of Engineering, Bengaluru held on 20th  to 21st  October 2016.
    5. Sareen Sheik and G.K. Nagaraja, “Thermal, mechanical and morphological characteristics of silk fibre-reinforced PVA and PVP hybrid composite films” in the International Conference on Advanced Materials and Technology (ICMAT-2016) , organized by Sri Jayachamarajendra College of Engineering, (SJCE), Mysore, held on 26th to 28th May 2016.

    Workshop Attend

    1. One day workshop “Pre-Conference Tutorials” at R. V. College of engineering, Bengaluru, on 20th October 2016.
    2. Orientation workshop on Radiation-It’s Applications in Physical, Chemical and Life Sciences organized by Mangalore University, Department of Studies in Physics, Mangalagangothri and UGC-DAE Consortium for Scientific Research, Kolkata Centre on June 24th-26th, 2015.
    3. One Day National Symposium in Recent Advances in Chemical Science (NSRACS-2013) held in the Department of Chemistry, Mangalore University, Mangalagangothri on 30th April 2013.
    4. Workshop on ‘Jeeva vaividya’ organized by Pilikula Regional Science center in collaboration with St. Agnes College on Feb 25th 2010. 
    5. State Level Seminar on Conservation of Natural Resources and Waste Management held on 23rd and 24th of Sep. 2009 at St. Agnes College, Mangalore.

    Awards and Achivements

    Best Paper award in the National Conference on Pure and Applied Chemistry (NACOPAC-2014) organized by the Dept. of Studies in Chemistry, Manasagangothri, Mysore.

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Chemistry Lab

The chemistry department has very good infrastructure with a working area of 2000 plus sq ft consisting chemistry laboratory and solution preparation room. The department has a VTU recognized research centre which has got a separate research laboratory with modern equipments and it offers Ph.D and M.Sc (Engg) by research degrees in the chemistry and related fields. The Department maintains a wide array of sophisticated instrumentation necessary for modern chemical analysis. Among department instruments are Spectrophotometer/ colorimeter, Rotary evaporator, pH meter, Conductivity meter, potentiometer, Water deionizer plant, distillation plant, Lyophiliser, melting point apparatus, Hot air oven, deep freezer, Autoclave, Centrifuge, Flame Photometer Water bath/ Oil bath etc.

coming soon

International Journal Papers

P.S. Manjula, B. K. Sarojini , B. Narayana, C. G. Darshan Raj ,An exploration on the synthesis and bio-applications of derivatives of heterocyclic mannich bases, J Fundam Appl Sci., vol. 8(1), pp. 115-175, 2016
R Srinivasan, B Narayana,B K Sarojini, V Bhanuprakash,C G DarshanRaj ,S. N Prakash, Design and synthesis of novel spiro-piperidinylpyrazolone derivatives and their potential antiviral activity, Let. Drug.Dis.Des.,vol. 13 no. 2, pp. 149-160, DOI: 10.2174/1570180812666150630182740. (Scopus Indexed Journal, Impact factor 0.78)

International Journal Papers

B K Sarojini, P S Manjula, C G Darshan Raj, In vivo neuroprotectionstudy of two 1,2,4- triazole derivatives in Drosophila melanogaster Oregon K flies, Journal of Pharmacy Research,vol. 9 no. 6,pp. 351-358, 2015
M Manjunath, P Ashok, S Apoorva, C G Darshan Raj, Rama Mohan H, Hari N. P,Synthesis and antiproliferative properties of isoxazole analogs containing dibenzosuberane moiety, Med Chem Res, DOI 10.1007/s00044-015- 1497-3 . (Scopus Indexed Journal, Impact factor 1.04)
P S. Manjula, B K. Sarojini, C G Darshan Raj,Ganesh, In vivoantioxidative stress measurement of a 1,2,4 Triazole derivative in Drosophila melanogaster Oregon K flies, Der PharmaChemica, vol. 7 no. 11, pp.70-78, 2015(Scopus Indexed Journal, Impact factor 0.48)

International Journal Papers

B G Krishna,, B K Sarojini, and C G DarshanrajSynthesis, characterization, molecular docking and evaluation of antibacterial, antiproliferative, and anti-inflammatory properties of new pyridinyl substituted triazole derivatives, Der PharmaChemica, vol. 6 no. 4, pp. 345-361, 2014(Scopus Indexed Journal, Impact factor 0.48)
B G Krishna, B K Sarojini, K Umesha, C G Darshanraj, Synthesis, characterization, molecular docking and evaluation of antimicrobial, antiproliferative, and anti-inflammatory properties of new 4-biphenyl substituted thiazolyl-pyridin- 2-aminederivatives , Der PharmaChemica, vol. 6, no. 4, pp.233-243, 2014(Scopus Indexed Journal, Impact factor 0.48)
K. E. Manojkumar , S. Sreenivasa, N. R. Mohan, P. A. Suchetan,, C. G. DarshanRaj,and H. Raja Naika, 2-[5- (2-fluorophenyl)- 3-(trifluoromethyl)- 1H-pyrazol- 1-yl] benzoic acid: Synthesis, Characterization and Pharmacological Evaluation, J. of Appli. Chem , vol. 3, no.1, pp. 64-73, 2014
M Manjunath, S,VijayC G Darshan Raj, A. S Paniraj, S Vadiraj, Gopinath, H Rama Mohan and N P Hari, Synthesis and Antimicrobial Properties of 1,3,4-Oxadiazole Analogs Containing Dibenzosuberane Moiety,J. Braz. Chem. Soc., vol. 25 no. 1, pp. 104-111, 2014(Scopus Indexed Journal, Impact factor 1.13)
B Reethi, C G Darshan Raj, H B Lingaraju, K Shyam Prasad,Effect of chlorogenic acid content in roasted coffee on in vitro antioxidant efficiency, J of Phar. Res, vol. 8, no. 1, pp. 20-23,2014
C. G. Darshan Raj, BalladakaKunhannaSarojini ,MoodalakoppaluKyathegowda Ramakrishna , Saraf R Ramesh , HanumanthappaManjunatha. In vivo peritoneal antiangiogenesis and in vitro antiproliferative properties of some bischalcone derivatives, Med. Chem. Res. DOI: 10.1007/s00044-011- 9551-2, 2014(Scopus Indexed Journal, Impact factor 1.04)

International Journal Papers

B. K Sarojini , K. Umesha , C. G Darshan Raj , V. Bhanuprakash R. Yogisharadhya , R. Raghavendra , M.T H Khan. In vitro and in silico biological studies of novel thiazolo[3,2- a]pyrimidine-6- carboxylate derivatives,Med. Chem.Res, DOI 10.1007/s00044-013- 0606-4, 2013(Scopus Indexed Journal, Impact factor 1.04)
E S SindhuPriya , C G Darshan Raj, K Shyam Prasad, H B Lingaraju, Neuroprotective property of Bromelain on focal ischemia and reperfusion induced cerebral injury in rats,Indo American Journal of Pharm Res, vol.3, no.7,pp. 181-197, 2013
M Manjunath,C. G. Darshan Raj,H Rama Mohan , N P Hari. , Synthesis and biological evaluation of cyclopentenone derivatives. JPR:BioMedRx: An Int. J, vol.1, no.9, pp. 865-868. 2013
M. Manjunath,S Vijay ,C. G Darshan Raj, A. S Paniraj, S Vadiraj. Gopinath, H Rama Mohan , N P Hari, Synthesis and Antimicrobial Properties of 1,3,4-Oxadiazole Analogs Containing Dibenzosuberane Moiety, J. Braz. Chem. Soc., Vol. 21, No. 6, pp. 1-8, 2013.(Scopus Indexed Journal, Impact factor, Impact factor 1.13)
B Reethi, C G Darshan Raj, H B Lingaraju, K Shyam Prasad, G Akshatha, Studies on Antimicrobial Efficacy of Aqueous Extract of Some Medicinal Plants against Food Borne Pathogens, World Jof Pharmac. Res.vol. 3 no. 1, pp. 959-973, 2013.
C G Darshan Raj, B K Sarojini, V Bhanuprakash, R.Yogisharadhya, R Raghavendra, B E Kumarswamy. Evaluation of in vitro antiviral efficacy and cyclic voltametric studies of some curcumin analogs,Med ChemRes , DOI 10.1007/s00044-011- 9793-z. 2013 (Scopus Indexed Journal, Impact factor 1.04)
C G Darshan Raj, B. K Sarojini, E S SindhuPriya, Protective efficacy of crude methanol extract of ashitaba green tea against radiation induced oxidative stress in E.coli K12 bacteria, Int. J. of Natural Pro. Res.; vol. 2 no.2,pp. 39-43,2013
C G Darshan Raj, B K Sarojini, ES SindhuPriya M T H Khan, Effect of new biphenyl chalcone derivatives against gamma radiation induced oxidative stress markers in E .coli K 12 and evaluation of their antimicrobial activities.Der PharmaChemica, vol. 5, no.3, pp. 305-317, 2013. (Scopus Indexed Journal, Impact factor 0.48)

International Journal Papers

S. Samshuddin, B. Narayana, B. K. Sarojini, M. T. H. Khan, H. S.Yathirajan, C. G. Darshan Raj, R. Raghavendra. Antimicrobial, analgesic, DPPH scavenging activities and molecular docking study of some 1, 3, 5-triaryl- 2-pyrazolines. DOI: 10.1007/s00044-011- 9735-9- MCR Springer, 2012 (Scopus Indexed Journal, Impact factor 1.04)
H.-K.Fun, S.Arshad, B.K.Sarojini, U.A.Imran & B.G.Krishna, 3-Benzyl- 7-(2,4- dichlorophenyl)-4H- 1,3,4-thiadiazolo[2,3- c][1,2,4]triazin-4- one ActaCryst. E68, vol 45, pp. o1736-o1737, 2012 (Impact factor 0.38)

International Journal Papers

M. Vidyagayathri, C. G. Darshan Raj, B. K. Sarojini, S. Srinivasa, R. Ragavendra. Synthesis, characterization, evaluation of antioxidant and antimicrobial properties of new N/O-substituted pyrazolone derivatives of Baylis-Hillman acetates, Journal of Pharmacy Research, vol.4 no.7, pp. 2012-2015, 2011.
C. G. Darshan Raj, B. K. Sarojini, M. K. Ramakrishna, S. R. Ramesh, B. Narayana, Ganesh Sanjeev. Protective effect of a synthetic bischalcone derivative (Curcumin analogue) against electron beam radiation induced oxidative stress in Drosophila melanogaster. J. of Phar. Res, vol.4, no.7, pp. 2012-2015, 2011
C G Darshan Raj, B K Sarojini,SubramanyaHeggade, S Srinivasa , V. Bhanuprakash , R. Yogisharadhya. Synthesis, characterization, assessment of in vitro antiviral, antiproliferative , antimicrobial and antioxidant properties of some heterocyclic chalcone derivatives.Med Chem Res, DOI 10.1007/s00044-012- 0193-9,2011(Scopus Indexed Journal, Impact factor 1.04)
B. K. Sarojini, C. G. Darshan Raj, M .K. Ramakrishna, S.R. Ramesh, In silico studies of (2E,5E)-2,5- bis(3-methoxy- 4-hydroxy- benzylidene) cyclopentanone on proteins AChE and BChE involved in Alzheimer's disease and ameliorative effects on paraquat induced oxidative stress markers in Drosophila melanogaster, Lett. Drug. Discov. & Design, 8,260-2672011, 2011(Scopus Indexed Journal, Impact factor 0.78)
C G Darshan Raj, B K Sarojini, R Raghavendra. Evaluation of in vivo antidiabetic efficacy of 2E,5E-2,5- bis(4-hydroxy- 3-methoxybenzylidene)cyclopentanone a curcumin analogs and in silico inhibition of AMPK protein. Med Chem Res, DOI 10.1007/s00044-012- 0237-1, 2011(Scopus Indexed Journal, Impact factor 1.04)
Fun, H.K. Suhana A., Sarojini, B. K., MusthafaKhaleel V and Narayana B. (2E )-3- (3- Benzyloxyphenyl)-1- (2-hydroxy- 5-methylphenyl)prop- 2-en- 1-one, Acta Cryst. vol. 61 no.3,pp. 1372–1373,2011, (Impact factor 0.38)
Fun, H.K. Loh, W.S., Sarojini, B. K., MusthafaKhaleel V and Narayana B. (2E )-3- [3- (Benzyloxy)phenyl]-1- (2-hydroxyphenyl)prop- 2-en- 1-one. Acta Cryst. vol. 46 no. 8, pp.1313–1314. 2011, (Impact factor 0.38 )
Fun, H.K. Suhana A., Sarojini, B. K., MusthafaKhaleel V and Narayana B. (2E )-1- (2-Hydroxy-5- methylphenyl)-3- (4-methoxyphenyl) prop-2- en-1- one.Acta Cryst. vol. 36 no.1,pp. 67, 1248–1249, 2011, (Impact factor 0.38)
Jasinski, Jerry P., Butcher ,Ray J., MusthafaKhaleel V., Sarojini, B. K. and Yathirajan, H.S.(E )-3- (3,4-Dimethoxyphenyl)- 1-(2- hydroxyphenyl)prop-2- en-1- one, Acta Cryst.vol. 67 no. 2,pp. E67, o845, 2011, (Impact factor 0.38)
Jasinski. Jerry P., Butcher. Ray J., MusthafaKhaleel, V. Sarojini, B. K. and Yathirajan, H.S. (2E )-3- (2-Anthracen- 2-yl)- 1-(2- hydroxyphenyl)prop-2- en-1- One, Acta Cryst.vol. 51 no.3,pp. 795, 2011, (Impact factor 0.38)
Jasinski.Jerry P, Butcher, Ray J., Yathirajan, H. S., Sarojini. B.K. andMusthafaKhaleel, V.(2E )-3- (4-Chlorophenyl)- 1-(4- hydroxyphenyl)prop-2- en-1- one Acta Cryst. vol. 67 no.3,756. 2011, (Impact factor 0.38)

International Journal Papers

B.K. Sarojini, M. Vidyagayatri, C.G. Darshanraj,B.R.Bharath, H. Manjunatha, DPPH scavenging assay of novel 1,3-disubstituted- 1H-pyrazol- 5-ols and their in silico studies on some proteins involved in Alzheimer’s disease signaling cascade, Letters in Drug Dis.& Des. vol. 7, no. 11, pp. 214-224, 2010. (Scopus Indexed Journal, Impact factor0.78)
B.K.Sarojini, B. G.Krishna ,C. G. Darshanraj B. R. Bharath , H. Manjunatha. Synthesis, characterization, in vitro and molecular docking studies of new 2,5-dichloro thienyl substituted thiazole derivatives for antimicrobial properties, Eur. J. Med.Chem.vol.45,pp. 3490-3496, 2010. (Scopus Indexed Journal, impact factor 3.39)
M.K. Ramakrishna, S.R. Ramesh, C.G. Darshan Raj, B.K. Sarojini. Neuroprotective activity of phytochemical combination of Quercetin and Curcumin against paraquat induced oxidative stress markers in Drosophila melanogaster. Dros. Inf. Serv.Vol. 93, pp. 147-148,2010
Hongqi Li, B. K. Sarojini, C. G. Darshan Raj , L. N. Madhu and H. S. Yathirajan. (E)-3- (3- Bromophenyl)-1- (4-methylphenyl) prop-2- en-1- one)Acta Cryst., vol43. E64, 2238, 2008. (Impact factor 0.38)
B. K. Sarojini, H. S. Yathirajan, K. Mustafa, H. Sarfraz&M. Bolte . (2E)-1- (2- Hydroxyphenyl)-3- [4-(methylsulfanyl)phenyl]prop- 2-en- 1-one. Acta Cryst. vol. 62 no. 8, pp. 4448. 2007, (Impact factor 0.38)
B. K. Sarojini, H. S. Yathirajan, K. Mustafa, H. Sarfraz&M. Bolte, (2E)-1- (2-Hydroxyphenyl)-3- (4-methoxyphenyl)prop- 2-en- 1-one. Acta Cryst. vol. 67 no. 9 , pp.E63, 4477 . 2007 (Impact factor 0.38)
B. K. Sarojini, K. Mustafa, B. Narayana, H. S. Yathirajan&M. Bolte .2-Bromo- 5- methoxybenzohydrazide. Acta Cryst. vol. 67 no. 9,pp. o4419, 2007, (Impact factor 0.38)
B. Narayana, K.Mustafa, B. K. Sarojini, H. S. Yathirajan&M. Bolte . (2E) -1 -(2- Thienyl)-3- (2,3,5-trichlorophenyl)prop- 2-en- 1-one. Acta Cryst. vol. 67 no. 4, pp. 4422- 4423, 2007, (Impact factor 0.38)
B. K. Sarojini, B. Narayana, K. Mustafa, H. S.Yathirajan and M.Bolte.5-Diethylamino- 2-[(Z)-(4- methyl-3- nitrophenyl)iminomethyl]phenol ActaCryst.vol. 62 no. 6 ,pp. 4782, 2007, (Impact factor 0.38)

International Journal Papers

Application no - 3731/CHE/2013
Date of filing - 23/08/2013
Title - Herbal Composition for obesity Management

International Conferences Papers

K.Umesha, C. G. Darshan Raj, B.K Sarojini, Mahmud T. H. Khan. “Evaluation of in vivo antidiabetic efficacy of (2Z) 2-[(3,4- difluorophenyl)methylidene]-5- (4-methoxyphenyl)- 7-methyl-3- oxo-2,3- dihydro-5H- [1,3]thiazolo[3,2-a]pyrimidine- 6-carboxylate and in silico inhibition of AMPK protein”. presented (oral) at International symposium on Challenges in drug discovery programm, 2011 held on 16-17 Feb 2011 at KSOU, Mysore

Journal Publications

C. G. DarshanRaj ,BalladakaKunhannSarojini , BasavapattanaRudreshBharath. In vivo peritoneal antiangiogenesis, “in vitro antiproliferative and in silico neuroprotective properties of (2E,5E)-2,5- bis(3-methoxy- 4-hydroxy- benzylidene) cyclopentanone”. presented (oral) at international conference on frontiers in biological Science-2010 held on 2-3 Oct 2010 at Rourkela
K. Umesha, B. K. Sarojini, C. G. Darshan Raj, V MusthafaKhaleel, V.BhanuprakashRaghavendra R. “One pot synthesis, characterization, antimicrobial and antiviral studies on new thiazolopyrimidine carboxylate derivatives”. Presented at international conference on frontiers in biological Science-2010 held on 2-3 Oct 2010 at Rourkela.
B. K. Sarojini, C. G. Darshan Raj, Narayana and Ganesh Sanjeev, “Amelorative Effect of Bischalcone on Gamma Radiation Induced Oxidative Stress in E.coli-K12”. presented Asia Pacific Symposium on radiation Chemistry held on 14-17 september -2010 at Lonavala- APSRTC-2010, RC-54
C. G. Darshan Raj, B. K. Sarojini, V Musthafakhaleel, S. R. Ramesh, M .K. Ramakrishna, B. Narayana and Ganesh Sanjeev. “Radioprotective Efficacy of BisarylideneCyclopentanone on Electron Beam Radiation Induced Oxidative Stress in Drosophila melanogaster”. Asia Pacific Symposium on radiation Chemistry held on 14-17 september -2010 at Lonavala- APSRTC-2010, RC-55
B. K. Sarojini, C. G. Darshan Raj, S. R. Ramesh, M. K Ramakrishna In vivo anti-angiogenic effect of novel 2E,5E-bis(4- flurobezylidene)-cyclopentanone on mouse Ehrlich Ascites Tumor cells 33rd All India \ Cell Biology Conference 2009 & International Workshop on Cell cycle Regulation AICBC2009 held on Dec. 10-13, 2009 at School of Life Sciences, University of Hyderabad, India AICBCP129
B.K.Sarojini, C.G.Darshan Raj, B.E. Kumaraswamy, B.Narayana, “Evaluation of the antioxidant activity of new bisbenzylidenecyclopentanone derivatives by cyclic voltammetry”, International conference on Recent advances in Industrial Electrochemical Science and Technology ICRAIEST-2009 held on Nov. 05-07, 2009 at Department of Chemistry, Mangalore University, India PP-52
Darshan Raj C G , Sarojini B K, Ramesh S R, Ramakrishna M K, Narayana B, Ganesh Sanjeev. “Protective effect of curcumin analogue on electron beam radiation induced oxidative stress in drosophila melanogaster”.4 th International Symposium on Current trends in Drug Discovery Research CTDDR-2010 held on Feb. 17-21, 2010 at CDRI- Lucknow, India. Abstracted in Medicinal Chemistry Research 2010, vol. 19, s67-63.
Darshan Raj C G , Sarojini B K, Vidyagayatri M, Ramesh S.R Ramakrishna M K, H.Manjunath, “In vivo anti-angiogenic effect and in vitro anti proliferative property of novel bis[2E,5E-bis(4- hydroxy-3- methoxybezylidene)-cyclopentanone] on mouse Ehrlich Ascites Tumor[EAT], Hep- G2 and Hela cell lines”.3rd International Conference on Genetic and Molecular Diagnosis in Modern Medicine and Biology-2010, Feb. 27-1st march, 2010 at Yenepoya University, India. Abstract No.102.
B. K. Sarojini, C. G. Darshan raj, S. R Ramesh, M. K Ramakrishna, “in vivo anti- angiogenic effect of novel 2E,5E-bis(4- flurobenzylidine)-cyclopentanone on mouse ehrlich ascites tumour”.33 d All India Cell biology conference2009 and International workshop on cell cycle regulation.AICBC-2009 held on Dec.10-13,2009 at school of life sciences,University of Hyderabad,Hyderabad,India.PP-129
B.K.Sarojini, C.G.Darshan Raj, B.E. Kumaraswamy, B.Narayana, “Evaluation of the antioxidant activity of new bisbenzylidenecyclopentanone derivatives by cyclic voltammetry”,International conference on Recent advances in Industrial Electrochemical Science and Technology ICRAIEST-2009 held on Nov. 05-07, 2009 at Department of Chemistry, Mangalore University,India PP-52
B. K. Sarojini, C. G. Darshan raj, M Vidyagayatri, S. R Ramesh, M. KRamakrishna,“Synthesis, characterization DPPH scavenging assay, In vivo neroprotectivestudies of new 1,3-disubstituted- 1H-pyrazol- 5-ols on Drosophila model system and In silico on proteins involved in Alzheimer’s disease signaling cascade and in vivo neuroprotective studies on Drosophila model system”.78 th annual meeting Society of Biological Chemists(India) held on 30 th &1 st Nov, 2009 At NCCS & University of Pune, India,PP- 170.
B.K.Sarojini , B.NarayanaN.SuchethaKumari , C.G.Darshan Raj, L.N.Madhu “ Studies on Antioxidant property of new Chalcone and Bischalcone derivatives” International conference on Frontiers in Chemical research ICFCR-2008 held on Dec. 28-31, 2008 at Department of Chemistry, Mangalore University,India OP-20
B.K.Sarojini, Mustafa Khaleel, C.G.Darshan Raj, L.N.Madhu “Studies on Antioxidant property of (2E)-3- (substituted aryl)-1- (2-hydroxyphenyl)- prop-2- en-1- ones”International conference on Frontiers in Chemical research ICFCR-2008 held on Dec. 28-31, 2008 at Department of Chemistry, Mangalore University, India PP-20
B.K.Sarojini, B.G.Krishna, C.G.Darshan Raj ‘Synthesis, characterization and evaluation of biological property of new thiazole derivatives’International conference on Frontiers in Chemical research ICFCR-2008 held on Dec. 28-31, 2008 at Department of Chemistry, Mangalore University, India PP-88
B.K.Sarojini, V.MustafaKhaleel, C.G.DarshanRaj, S.Sreenivasa, “Microwave Assisted Synthesis of New Chalcone derivatives, Characterization and evalution of antifungal and antibacterial properties ”International conference on advanced materials ICAM-2008 held on Feb 18-21 2008 at School of Chemical Sciences MG University, Kottayam, Kerala, India GCP 04 –Page No. 207.
C. G. Darshan Raj, B. K. Sarojini , S. R. Ramesh , M .K. Ramakrishna , “Radioprotective effect of bischalcone on electron beam radiation induced oxidative stress in Drosophila melanogaster”, presented (oral) at Drosophilla Fly meeting-2010 held on 19-20 Nov 2010 at Dept of Zoology, University of Mysore.
K.Umesha, B.K. Sarojini, C. G. Darshan Raj, E.S.sinduPriya, “Green synthesis of new thiazolo[3,2-b][1,2,4]triazole derivatives microwave irradiation and their antioxidant studies”.International conference of recent advances in Material Science and technology 2013 (ICRAMST-13) held at NITK surathkal Jan 17-19 2013. OP-75
B.J.Mohan, B.K.Sarojini, C.G.Darshan Raj“Synthesis, characterization, evaluation o fantimicrobial properties of 3-methyl- 5(4h)- pyrazolone derivatives”. International conference on recent advances in Material Science and technology 2013 (ICRAMST-13) held at NITK Surathkal Jan 17-19 2013 OP-35.
K.Umesha, C. G. Darshan Raj, B.K. Sarojini, Microwave assisted synthesis, characterization, evaluation of in vitro antibacterial and antioxidant activities of new imidazo[2,1-b]thiazole derivatives.International conference on synthetic and structural Chemistry, held at Mangalore University, Dec. 8-10 2011 pp 160.
M. Vidyagayatri, C. G. Darshan Raj, B.J. Mohan, B.K. Sarojini,Synthesis, characterization, evaluation of antioxidantand antimicrobial properties of new n/o-substitutedpyrazolone derivatives of baylis-hillman acetates. . International conference on synthetic and structural Chemistry, held at Mangalore university, Dec. 8-10 2011, pp 170.

National Conferences Papers

C G Darshan Raj, B K Sarojinia, Vidyagayathri M.M.T. Hassan Khan, “In vivo antidiabetic activity and in silico studies on adenosine monophosphate-activated protein kinase (AMPK) of (2E,5E)-2,5- bis (4-hydroxy- 3- methoxybenzylidene) cyclopentanone” presented (oral) at state level conference on mesmerizing fields of Biotechnology(MFOB) held on April 08-09 2011 at SDM, Ujire, Karnataka, India.
B. K. Sarojini, C. G Darshan raj, B. Narayana, S. Ganesh, M.K. Ramakrishna, S. R Ramesh, “In vivo antioxidant property of novel (2E, 5E)-2,5- bis(3-methoxy- 4-hydroxy- b enzylidene) cyclopentanone on Drosophila melanogaster”. National conference on recent trends in chemical research held on 8-10 th Mar 2010 at Dept of Chemistry, National Institute of Technology, Karnataka. Oral presentation no 15
B. K. Sarojini, C. G. Darshan raj, S.K Ajay, “A review on effect of Turmeric (Curcumin) on Alzheimer Disease (AD)”, 5 th KannadaVijnanaSammelana 15-17th Sept 2009, Mangalore University, Mangalore, Karnataka, India.
B.K.Sarojini , C.G.Darshan Raj, V.MustafaKhaleel ”Studies on the synthsis,characterization and SHG efficiency of 1- (4- hydroxyphenyl) -3- (3-bromophenyl)-prop- 2-en- 1-one – a new NLO material”National level Symposium on Radiattion and Photochemistry held on March 12-14, 2009 at P.G. Department of Physics, Kumaun University Nainital PC-08.
B.K.Sarojini, Vidyagayatri M, C.G.Darshan Raj, ‘Studies on DPPH scavenging capacity assay of new1,3-disubstituted -1H-pyrazol- 5-ols’ State level conference on Emerging trends in Medicinal chemistry held on March 6-7 th , 2009 at P.G. Department of Chemistry, SDMC Ujire OP-03.
M. Vidyagayatri, C. G. Darshan Raj, B. K. Sarojini, “Synthesis characterization, evaluation of antiproliferative and antimicrobial properties of New Pyrazole derivatives”. National conference Chemistry: challenges and opportunities, (NCCCO-2012) held at St Joseph’s College Bangalore, Feb. 16-18, 2012 OCM-1.

Research Interested Groups

Name of the Facility, Department Description of Facility Major Equipment Specification
Radioprotection studies lab Synthesis and purification of compounds Rotary evaporator 250 m
Cold centrifuge 2.5ml and 50 ml
Deep freezer -80
Lyophiliser NA
UV trans illuminator NA
Fume hood cup board 2 working space
MP apparatus Digital
Drosophila model system research lab Heating mantel Stirring and heating
Oil bath 2 L capacity
Water bath Digital
Vacuum pump
Biochemical studies Inoculation chamber Single user
Incubator 50 L volume
Incubator 50 L volume
Enzymology Incubator 50 L volume
Gel rock 2 PAGE tilter
SDS PAGE unit with power pack 15 well
Gel electrophoresis 6 well
Deep freezer -80 -80
UV spectrophotometer UV range
Visible spectrophotometer Visible
Hot air oven Conventional

Invited Talks

Alternative model system for radioprotection studies” at SIPMS, Tumkur, on 29- Feb-2016 -Dr Darshan Raj C G
Research trends in Nanotechnology” at SMC, Tumkur on 15-04-2016

Funds Recieved

Studies on NLO and Liquid crystalline properties of some substituted chalcones and related compounds – 2003 -07: [CAYT] AICTE –Rs.10.5 lakhs [Grant No.1- 51/FD/CA/003/2003-04]
Physicochemical characteristics of water in Kaiga area - 2007- 10 : Nuclear Power Corporation of India-Rs.10.92 Lakhs [Grant No. NPICL/AD (RSA)/2007/M]- Co-PI.
In vitro studies on radioprotective effect of chalcone and its derivatives from synthetic and natural origin in bacteria’ -2008 -11: Board of Research in Nuclear Sciences - Rs.11.81Lakhs [Grant No.2008 /34/05-BRNS/457]- PI.
Isolation, purification, characterization of trypsin from fish visceral wastes of fish processing Industries -2009-12: Ministry of Earth Sciences [DST] – Rs. 30.17 Lakhs[Grant No. MoES/11-MRDF/1/63/P/08] – PI.
Studies on radioprotective effect of phytochemicals of AnisomelesindicaKuntze -2009-12: Board of Research in Nuclear Sciences (BRNS) [No.2009/34/27/BRNS/1995]- Rs.17.379 Lakhs [Co-PI].

Labs Established under funding schemes

Radioprotection studies lab
Drosophila model system research lab
Enzymology

Research Guidance

Research Guide Ph.D. Research Scholar Name Research Area University Status
Prof. B K Sarojini Mustafa Khaleel V Organic chemistry VTU, Belgaum Ongoing
Darshan Raj C G Organic chemistry VTU Completed
Umesha K Organic chemistry VTU Completed
Krishna B G Organic chemistry VTU Completed
Vidyagayathri M Organic chemistry VTU Completed
Mohan Organic chemistry VTU Ongoing
Manjula P S Organic chemistry VTU Ongoing
Imran Organic chemistry VTU Ongoing

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